Membrane Protein Microarray Screening ServiceOnline Inquiry
Cell membranes, which are widespread in cells, partition cells into different sizes and support communication between cells, therefore, are essential in various biological processes. Currently, many of the most important drug targets in medicine are discovered based on membrane proteins. For example, cell membrane proteins such as G protein-coupled receptors (GPCRs), ion channels are the main targets for the design of large-molecule antibody drugs and small-molecule drugs.
Overview of membrane protein microarray
The protein microarray technology, including membrane protein microarrays, was inspired by the previously developed DNA microarray technology, which is constructed by immobilizing hundred of thousand of oligonucleotides on a small slide and provides a high-throughput method for studying alterations in gene expression in cells or tissues. Similarly, membrane protein microarray contains large numbers of membrane proteins, such as single-pass transmembrane proteins, multi-pass transmembrane proteins, and GPI-anchored proteins, assembled to meet the needs of different applications.
Membrane protein microarray service at Creative Proteomics
Membrane protein microarray technology has emerged as an important technical tool for membrane protein research. With the unique technical design, this technique not only solves the problem of membrane protein conformation and activity but also allows high-throughput cell membrane binding screening work. To better and efficiently assist researchers and professionals in studying cell membrane proteins, Creative Proteomics offers a membrane protein microarray screening service. The service can be used for the determination of small molecules, peptides, antibodies, proteins, and other ligands to facilitate membrane protein-based drug development and mechanism studies.
- Workflow of our service
-Screening condition measurement. Customers simply send us their target analytes and we will optimize the best screening conditions (time, temperature, pH, etc.) for testing based on the analyte's characteristics.
-Membrane protein microarray screening. Identification of binding targets by membrane protein microarrays.
-Reliable validation of binding targets.
- Sample requirements
-Protein/peptide/small molecule: At least 3μg per sample
-Antibody: At least 3μg per sample (>0.1mg / mL)
-DNA/RNA: At least 300μL per sample ( >2μM)
-Other fluids: Please contact us
Applications of our membrane protein microarray services
- Antibody and related molecule discovery
- Complex ligand screening
- Vaccine development
- Epitope mapping
Advantages of our services
- A team of experts in molecular biology, proteomics and biochemistry
- A well-established membrane protein microarray platform with various membrane proteins
- Compatible with almost biotherapeutics
- Fast project turnaround time, from 3 weeks
Creative Proteomics' membrane protein microarray service supports reliable and effective membrane protein research. What types of molecules can be screened using our membrane protein microarray technology? What is the sensitivity of our membrane protein microarrays? What information will I receive? And how long will this service take? If you have any of these questions, please don't hesitate to contact us. Our professional technical staff will contact you as soon as possible and provide you with professional answers.
* For Research Use Only. Not for use in diagnostic procedures.